<PAGE>
                        UNITED STATES                 
             SECURITIES AND EXCHANGE COMMISSION             
                   WASHINGTON, D.C. 20549           
                                                  
                       SCHEDULE 13D               
                                                      
           UNDER THE SECURITIES EXCHANGE ACT OF 1934    
                                                     
                                                      
                                                     
                                                
                                                         
                       Brainstorm Cell Therapeutics Inc.
                 ---------------------------------------------
                              (Name of Issuer)

                        Common Stock, $0.00005 par value
                 ---------------------------------------------
                        (Title of Class of Securities)

                                 10501E201
                 ---------------------------------------------
                               (CUSIP Number)

                               Joseph P. Daly
                             497 Circle Freeway
                           Cincinnati, Ohio 45246
                              (513) 943-7100
    ------------------------------------------------------------------------
 (Name, Address and Telephone Number of Person Authorized to Receive Notices
                               and Communications)


                           November 15, 2019
    ------------------------------------------------------------------------
             (Date of Event which Requires Filing of this Statement)

If the filing person has previously filed a statement on Schedule 13G to report
the acquisition that is the subject of this Schedule 13D, and is filing this
schedule because of Sections 240.13d-1(e), 240.13d-1(f) or 240.13d-1(g), check
the following box. [ ]

NOTE: Schedules filed in paper format shall include a signed original and five
copies of the schedule, including all exhibits. See Section 240.13d-7 for other
parties to whom copies are to be sent.

The information required on the remainder of this cover page shall not be deemed
to be "filed" for the purpose of Section 18 of the Securities Exchange Act of
1934 ("Act") or otherwise subject to the liabilities of that section of the Act
but shall be subject to all other provisions of the Act (however, see the
Notes).

<PAGE>


<Table>
<S>     <C>                                                                             <C>

-----------------------------------------------------------------------------------------------------------
CUSIP No.      10501E201                           13D
              -----------                              
-----------------------------------------------------------------------------------------------------------

    1   NAMES OF REPORTING PERSONS

            Joseph P Daly

        I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (entities only)
-----------------------------------------------------------------------------------------------------------
    2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                                                                    (a) [ ]
                                                                                                    (b) [ ]
-----------------------------------------------------------------------------------------------------------
    3   SEC USE ONLY

-----------------------------------------------------------------------------------------------------------
    4   SOURCE OF FUNDS (See Instructions)

                PF
-----------------------------------------------------------------------------------------------------------
    5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)         [ ]
-----------------------------------------------------------------------------------------------------------
    6   CITIZENSHIP OR PLACE OF ORGANIZATION

            United States
-----------------------------------------------------------------------------------------------------------
       NUMBER OF SHARES             7    SOLE VOTING POWER

         BENEFICIALLY                    1,035,181
                             ------------------------------------------------------------------------------
           OWNED BY                 8    SHARED VOTING POWER

        EACH REPORTING                   -0-
                             ------------------------------------------------------------------------------
         PERSON WITH                9    SOLE DISPOSITIVE POWER

                                         1,035,181
                             ------------------------------------------------------------------------------
                                   10    SHARED DISPOSITIVE POWER

                                         -0-
                             ------------------------------------------------------------------------------
   11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

               1,035,181
-----------------------------------------------------------------------------------------------------------
   12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions)        [ ]
-----------------------------------------------------------------------------------------------------------
   13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                4.58%
-----------------------------------------------------------------------------------------------------------
   14   TYPE OF REPORTING PERSON (See Instructions)

                  IN
-----------------------------------------------------------------------------------------------------------
</TABLE>

        

<PAGE>


<Table>
<S>     <C>                                                                             <C>

-----------------------------------------------------------------------------------------------------------
CUSIP No.      10501E201                            13D
              -----------                              
-----------------------------------------------------------------------------------------------------------

    1   NAMES OF REPORTING PERSONS

            Karina Daly

        I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (entities only)
-----------------------------------------------------------------------------------------------------------
    2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                                                                    (a) [ ]
                                                                                                    (b) [X]
-----------------------------------------------------------------------------------------------------------
    3   SEC USE ONLY

-----------------------------------------------------------------------------------------------------------
    4   SOURCE OF FUNDS (See Instructions)

                PF
-----------------------------------------------------------------------------------------------------------
    5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)         [ ]
-----------------------------------------------------------------------------------------------------------
    6   CITIZENSHIP OR PLACE OF ORGANIZATION

            United States
-----------------------------------------------------------------------------------------------------------
       NUMBER OF SHARES             7    SOLE VOTING POWER

         BENEFICIALLY                    83,182
                             ------------------------------------------------------------------------------
           OWNED BY                 8    SHARED VOTING POWER

        EACH REPORTING                   -0-
                             ------------------------------------------------------------------------------
         PERSON WITH                9    SOLE DISPOSITIVE POWER

                                         83,182
                             ------------------------------------------------------------------------------
                                   10    SHARED DISPOSITIVE POWER

                                         -0-
                             ------------------------------------------------------------------------------
   11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

              83,182
-----------------------------------------------------------------------------------------------------------
   12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions)        [ ]
-----------------------------------------------------------------------------------------------------------
   13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                0.37%
-----------------------------------------------------------------------------------------------------------
   14   TYPE OF REPORTING PERSON (See Instructions)

                  IN
-----------------------------------------------------------------------------------------------------------
</TABLE>

     

<PAGE>

<Table>
<S>     <C>                                                                             <C>

-----------------------------------------------------------------------------------------------------------
CUSIP No.      10501E201                           13D
              -----------                              
-----------------------------------------------------------------------------------------------------------

    1   NAMES OF REPORTING PERSONS

            EssigPR Inc.

        I.R.S. IDENTIFICATION NOS. OF ABOVE PERSONS (entities only)
-----------------------------------------------------------------------------------------------------------
    2   CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (See Instructions)
                                                                                                    (a) [ ]
                                                                                                    (b) [X]
-----------------------------------------------------------------------------------------------------------
    3   SEC USE ONLY

-----------------------------------------------------------------------------------------------------------
    4   SOURCE OF FUNDS (See Instructions)

                WC
-----------------------------------------------------------------------------------------------------------
    5   CHECK BOX IF DISCLOSURE OF LEGAL PROCEEDINGS IS REQUIRED PURSUANT TO ITEMS 2(D) OR 2(E)         [ ]
-----------------------------------------------------------------------------------------------------------
    6   CITIZENSHIP OR PLACE OF ORGANIZATION

            Rincon, PR, USA
-----------------------------------------------------------------------------------------------------------
       NUMBER OF SHARES             7    SOLE VOTING POWER

         BENEFICIALLY                    137,565
                             ------------------------------------------------------------------------------
           OWNED BY                 8    SHARED VOTING POWER

        EACH REPORTING                   -0-
                             ------------------------------------------------------------------------------
         PERSON WITH                9    SOLE DISPOSITIVE POWER

                                         137,565
                             ------------------------------------------------------------------------------
                                   10    SHARED DISPOSITIVE POWER

                                         -0-
                             ------------------------------------------------------------------------------
   11   AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON

               137,565
-----------------------------------------------------------------------------------------------------------
   12   CHECK IF THE AGGREGATE AMOUNT IN ROW (11) EXCLUDES CERTAIN SHARES (See Instructions)        [ ]
-----------------------------------------------------------------------------------------------------------
   13   PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (11)

                0.61%
-----------------------------------------------------------------------------------------------------------
   14   TYPE OF REPORTING PERSON (See Instructions)

                  CO
-----------------------------------------------------------------------------------------------------------
</TABLE>
   

<PAGE>


         ITEM 1. SECURITY AND ISSUER.

        The class of equity security to which this statement relates is the
common stock (the "Common Stock"), $0.00005 value per share ("Share"), of
Brainstorm Cell Therapeutics Inc., a Delaware corporation (the "Issuer"). 
The address of the principal executive offices of the Issuer is 
1325 Avenue of Americas, 28th Floor, New York, NY 10019


         ITEM 2. IDENTITY AND BACKGROUND.

        NOTE: THE EXECUTION AND SUBMISSION OF THIS STATEMENT BY THE
PERSONS LISTED BELOW (THE "REPORTING PERSONS") SHALL NOT BE CONSTRUED AS A
STATEMENT OR ADMISSION THAT THE REPORTING PERSONS (I) ARE ACTING AS A GROUP
IN THE ACQUISITION OF THE SHARES, (II) COLLECTIVELY CONSTITUTE A "PERSON"
WITHIN THE MEANING OF SECTION 13(D)(3) OF THE SECURITIES EXCHANGE ACT OF 1934,
AS AMENDED (THE "ACT"), OR (III) FOR THE PURPOSES OF SECTION 13(D) OF THE ACT,
ARE THE BENEFICIAL OWNERS OF ANY SHARES OTHER THAN THE SHARES IN WHICH EACH
PERSON IS SPECIFICALLY IDENTIFIED IN THIS STATEMENT TO HAVE A BENEFICIAL
INTEREST.

(1) (a) Joseph P. Daly
(b) 497 Circle Freeway, Cincinnati, OH 45246
(c) Owner, Essig Research Inc.
(d) No
(e) No
(f) U.S.A.

(2) (a) Karina Daly
(b) 497 Circle Freeway, Cincinnati, OH 45246
(c) Administrator
(d) No 
(e) No
(f) U.S.A.

(3) EssigPR, Inc. is a C Corporation, controlled by Joseph P. Daly, which
provides technical consulting services.  The address of EssigPR is
36 CARR 413, Rincon, PR 00677.



ITEM 3. SOURCE AND AMOUNT OF FUNDS OR OTHER CONSIDERATION.

The source of funds used by the Reporting Persons are personal funds of
each such person with respect to the purchases of such person, except
the source of funds used for the purchases by EssigPR, Inc were from 
working captial. The Reporting Persons did not borrow any funds to acquire
their respective shares. The following table shows the APPROXIMATE amounts of
funds paid for the Shares by the Reporting Persons.


<TABLE>
<S>                                  <C>
Joseph P Daly                        $3,847,264


Karina Daly                             342,742


EssigPR, Inc.                           536,153

</TABLE>



<PAGE>


ITEM 4. PURPOSE OF TRANSACTION.

The Reporting Persons purchased the Shares for investment purposes.
The Reporting Persons are continuing to review the performance of
their investment and their investment alternatives.  As part of their
ongoing review of their investment in the Shares, the Reporting Persons
may explore from time to time a variety of alternatives, including the
acquisition of additional securities of the Issuer or the disposition
of securities of the Issuer in the open market or in privately negotiated
transactions.  The Reporting Persons may explore other alternatives with
respect to their investment in the Shares, including but not limited to
an extraordinary corporate transaction involving the Issuer, changes in
the present board of directors or management of the Issuer, or changes in
the Issuer's business or corporate structure.  Although the foregoing
reflects activities presently contemplated by the Reporting Person with
respect to the Issuer, the foregoing is subject to change at any time,
and there can be no assurance that the Reporting Persons will take any
of the actions referred to above.

         Except as set forth in the preceding paragraphs, as of the date hereof,
         the Reporting Persons do not have any plan or proposal that relates to
         or would result in:

         (a) The acquisition by any person of additional securities of the
         Issuer, or the disposition of securities of the Issuer;

         (b) An extraordinary corporate transaction, such as a merger,
         reorganization or liquidation, involving the Issuer or any of its
         subsidiaries;

         (c) A sale or transfer of a material amount of assets of the Issuer or
         any of its subsidiaries;

         (d) Any change in the present board of directors or management of the
         Issuer, including any plans or proposals to change the number or term
         of directors or to fill any existing vacancies on the board;

         (e) Any material change in the present capitalization or dividend
         policy of the Issuer;

         (f) Any other material change in the Issuer's business or corporate
         structure;

         (g) Changes in the Issuer's charter, bylaws or instruments
         corresponding thereto or other actions which may impede the acquisition
         of control of the Issuer by any person;

         (h) Causing a class of securities of the Issuer to be delisted from a
         national securities exchange or to cease to be authorized to be quoted
         in an inter-dealer quotation system of a registered national securities
         association;

         (i) A class of equity securities of the Issuer becoming eligible for
         termination of registration pursuant to Section 12(g)(4) of the Act; or

         (j) Any action similar to any of those enumerated above.

         Notwithstanding the foregoing, the Reporting Persons reserve the right
         to effect any such actions as they may deem necessary or appropriate in
         the future.

         The information set forth in Item 3 of this Schedule 13D is hereby
         incorporated herein by reference.


        


         ITEM 5. INTEREST IN SECURITIES OF THE ISSUER.

(a) The Reporting Persons hereby report beneficial ownership, in the manner
hereinafter described, of 1,255,928 shares of the Issuer:


<TABLE>
<CAPTION>
                                            Percentage of
                             Number Of      Outstanding
Shares Held in the Name of   Shares         Security (1)
<S>                          <C>            <C>
Joseph P Daly              1,035,181        4.58%

   
Karina Daly                   83,182        0.37%


EssigPR Inc.                 137,565(2)     0.61%
                           ------------     -------

TOTAL                      1,255,928        5.56%

</TABLE>


(1) The foregoing percentages assume that the number of Shares of the Issuer
outstanding,as reported in the Issuer's 10-Q for the quarter ended
September 30, 2019 is 22,606,492 Shares (as of November 6, 2019).

(2) Shares are held by EssigPR,Inc., a C corporation controlled by
Joseph P. Daly

 
 (b) Joseph P. Daly has sole voting and dispositive power over his shares
enumerated in paragraph (a).  Karina Daly has sole voting and dispositive
power over her shares enumerated in paragraph (a).  EssigPR, Inc. has shared
voting and dispositive power over its shares enumerated in paragraph (a).



<PAGE>

(c)  Transactions for the 60 days prior to the date of this Schedule 13D :


<Table>
<Caption>

Person Who Effected the Transaction      Transaction Date      # of Shares Purchased (Sold)    Price per Share
<S>                                      <C>                    <C>                            <C>

Joseph P. Daly                               10/18/2019                    (3000)                   3.90
Joseph P. Daly                               10/18/2019                    (2000)                   3.92
Joseph P. Daly                               10/21/2019                    (1000)                   3.92
Joseph P. Daly                               10/21/2019                    (4000)                   3.90
Joseph P. Daly                               10/22/2019                    (1218)                   3.90
Joseph P. Daly                               10/24/2019                       (2)                   3.90
Joseph P. Daly                               10/29/2019                    10000                    3.61
Joseph P. Daly                               10/29/2019                    33500                    3.56
Joseph P. Daly                               10/30/2019                     3000                    3.61
Joseph P. Daly                               11/14/2019                      401                    3.61
Joseph P. Daly                               11/14/2019                    17500                    3.57
Joseph P. Daly                               11/15/2019                   162500                    3.59
Joseph P. Daly                               11/15/2019                   222500                    3.66
Karina Daly                                  09/30/2019                    (2000)                   3.92
Karina Daly                                  09/30/2019                    (2500)                   3.86
Karina Daly                                  10/09/2019                    (2000)                   3.91
Karina Daly                                  10/14/2019                    (1000)                   3.91
Karina Daly                                  10/15/2019                    (1000)                   3.94
Karina Daly                                  10/15/2019                    (1500)                   3.95
Karina Daly                                  10/16/2019                      (35)                   3.97
Karina Daly                                  10/17/2019                     (783)                   3.94
EssigPR                                      11/14/2019                      500                    3.66
EssigPR                                      11/14/2019                      138                    3.67
EssigPR                                      11/14/2019                     1626                    3.68
EssigPR                                      11/14/2019                      691                    3.69
EssigPR                                      11/14/2019                      180                    3.70
EssigPR                                      11/18/2019                     7000                    3.70
EssigPR                                      11/18/2019                     2030                    3.69
EssigPR                                      11/18/2019                      100                    3.65
EssigPR                                      11/18/2019                      300                    3.67


</Table>


             All transactions were effectuated through open-market purchases
             or a result of a counterparty's exercise of a derivatives contract

         (d) RIGHT TO RECEIVE OR POWER TO DIRECT: Not applicable.

         (e) DATE REPORTING PERSON CEASED TO BE 5% OWNER: Not applicable.

         ITEM 6. CONTRACTS, ARRANGEMENTS, UNDERSTANDINGS OR RELATIONSHIPS WITH
         RESPECT TO SECURITIES OF THE ISSUER.

                           None.


         ITEM 7. MATERIAL TO BE FILED AS EXHIBITS.

                           None.

                                   SIGNATURES

        After reasonable inquiry and to the best of my knowledge and belief, I
certify that the information set forth in this statement is true, complete and
correct.

Date: November 21, 2019
                                               /s/   Joseph P Daly
                                               ------------------------
                                               Print Name: Joseph P Daly



                                               /s/   Karina Daly
                                               ------------------------
                                               Print Name: Karina Daly


EssigPR, Inc.
By:                                            /s/   Joseph P Daly
                                               ------------------------
                                               Print Name: Joseph P Daly